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Metoclopramide may reduce plasma concentrations of atovaquone.

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Metoclopramide may cause a potentially fatal symptom complex called neuroleptic malignant syndromeNMSNMS has been reported in association with metoclopramide overdosage and concomitant treatment with another drug associated with NMSdiscontinue therapy immediately if symptoms occur.

Metoclopramide is used to relieve heartburn and speed the healing of ulcers and sores in the esophagustube that connects the mouth to the stomachin people who have gastroesophageal reflux diseaseGERDcondition in which backward flow of acid from the stomach causes heartburn and injury of the esophagusthat did not get better with other treatmentsMetoclopramide is also used to relieve symptoms caused by slow stomach emptying in people who have diabetesThese symptoms include nauseavomitingheartburnloss of appetiteand feeling of fullness that lasts long after mealsMetoclopramide is in a class generic atarax of medications called prokinetic agentsIt works by speeding the movement of food through the stomach and intestines.

NEVER USE METOCLOPRAMIDE IN LARGER AMOUNTS THAN RECOMMENDEDOR FOR LONGER THAN 12 WEEKSHigh doses or long-term use can cause a serious movement disorder that may not be reversibleThe longer you use metoclopramidethe more likely you are to develop this movement disorderThe risk of this side effect is higher in diabetics and older adultsespecially women

Metoclopramide oraltaken by mouthis used for 4 to 12 weeks to treat heartburn caused by gastroesophageal reflux in people who have used other medications without relief.

Metoclopramide may cause a potentially fatal symptom complex called neuroleptic malignant syndromeNMSNMS has been reported in association with metoclopramide overdosage and concomitant treatment with another drug associated with NMSdiscontinue therapy immediately if symptoms occur.

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