Resistance to ampicillin, chloramphenicol, kanamycin, sulfonamide, and streptomycin-spectinomycin was due to the production of a tem-1 penicillinase bla tem-1 , a type i chloramphenicol acetyltransferase cati , a type i 3 – o -aminoglycoside phosphotransferase aph 3 -i , a drug-resistant dihydropteroate synthase sul1 , and a 3 -9- o -aminoglycoside adenylyltransferase ant3 9 , respectively.
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Termination of polypeptide synthesis by binding to the bacterial 50S ribosomal subunit.
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