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Celebrex is not recommended in patients with severe renal insufficiency see warnings and precautions 5.

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Limited data from 3 published reports that included a total of 12 breastfeeding women showed low levels of CELEBREX in breast milkThe calculated average daily infant dose was 10-40 mcg/kg/dayless than 1of the weight-based therapeutic dose for a two-year old-childA report of two breastfed infants 17 and 22 months of age did not show any adverse eventsCaution should be exercised when CELEBREX is administered to a nursing womanThe developmental and health benefits of breastfeeding should be considered along with the mother’s clinical need for CELEBREX and any potential adverse effects on the breastfed infant from the CELEBREX or from the underlying maternal condition.

Tell your doctor about all your current medicines and any you start or stop usingespecially:

Avoid the use of CELEBREX in patients with severe heart failure unless the benefits are expected to outweigh the risk of worsening heart failureIf CELEBREX is used in patients with severe heart failuremonitor patients for signs of worsening heart failure.

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