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Safety in nine randomized comparative us clinical trials in patients with gerd included 1,473 patients on oral protonix 20 mg or 40 mg , 299 patients on an h 2 -receptor antagonist, 46 patients on another ppi, and 82 patients on placebo.

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The most commonly reported side effects were headachediarrheaand injection site thrombophlebitisin IV formulationsRef]

Pantoprazole is used to treat certain stomach and esophagus problemssuch as acid refluxIt works by decreasing the amount of acid your stomach makesThis medication relieves symptoms such as heartburndifficulty swallowingand persistent coughIt helps heal acid damage to the stomach and esophagushelps prevent ulcersand may help prevent cancer of the esophagusPantoprazole belongs to a class of drugs known as proton pump inhibitorsPPIs

There are no adequate and well-controlled studies in pregnant womenAdvise pregnant women of the potential risk of fetal harmBecause animal reproduction studies are not always predictive of human responsethis drug should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

More frequent side effects includediarrhea and nauseaSee below for a comprehensive list of adverse effects.

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