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Renal impairmentUse cautiondrug accumulation may occur with severe renal impairment.
Healthcare providers should inform patientstheir familiesand their caregivers about the benefits and risks associated with treatment with SARAFEM and should counsel them in its appropriate useHealthcare providers should instruct patientstheir familiesand their caregivers to read the Medication Guide and should assist them in understanding its contentsPatients should be given the opportunity to discuss the contents of the Medication Guide and to obtain answers to any questions they may have.
Fluoxetine can stay in your body for many weeks after your last dose and may interact with many other medicationsBefore using any medicationtell your doctor or pharmacist if you have taken fluoxetine in the previous 5 weeks.
In 2 placebo-controlled clinical trials for PMDDpatients treated with SARAFEM reported anxietynervousnessand insomniasee Table 3
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