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No overall differences in safety and efficacy were observed between the elderly and younger individualsand other reported clinical experience has not identified differences in responses between the elderly and younger patientsbut greater sensitivity of some older individuals cannot be ruled out.

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Use of NEXIUM in pediatric and adolescent patients 1 to 17 years of age for short-term treatmentup to eight weeksof GERD is supported by extrapolation of results from adequate and well-controlled studies for adults and safety and pharmacokinetic studies performed in pediatric and adolescent patientssee DOSAGE AND ADMINISTRATIONADVERSE REACTIONSCLINICAL PHARMACOLOGYand Clinical StudiesThe safety and effectiveness of NEXIUM for other pediatric uses have not been established.

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over 85,000 patients in 62 countries were evaluated in clinical trials of nexium and close to 746 million patient treatments were administered by the end of 2007 5.

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