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Don t know if this has already been covered – my husband had a small stroke in 2010, and was put on plavix by his neurologist.

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Since selective serotonin reuptake inhibitorsSSRIsand serotonin norepinephrine reuptake inhibitorsSNRIsaffect platelet activationthe concomitant administration of SSRIs and SNRIs with clopidogrel may increase the risk of bleeding.

LactationNot known whether drug is excreted in human milkbecause many drugs are excreted in human milk and because of potential for serious adverse reactions in nursing infants from clopidogrela decision should be made whether to discontinue nursing or to discontinue drugtaking into account importance of drug to mother.

The effect of proton pump inhibitorsPPIon the systemic exposure to the clopidogrel active metabolite following multiple doses of Plavix 75 mg evaluated in dedicated drug interaction studies is presented in Figure 1.

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