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Reglan s association to the development of td, especially with long-term use, necessitated the inclusion of a boxed warning, also called a black box warning, to the drug s label in 2009.

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Metoclopramide itself may suppressor partially suppressthe signs of TDthereby masking the underlying disease processThe effect of this symptomatic suppression upon the long-term course of TD is unknownThereforemetoclopramide should not be used for the symptomatic control of TD.

Metoclopramide should be discontinued in patients who develop signs or symptoms of TDThere is no known effective treatment for established cases of TDalthough in some patientsTD may remitpartially or completelywithin several weeks to months after metoclopramide is withdrawn.

Reglan Injectionmetoclopramide hydrochlorideUSPis indicated for the relief of symptoms associated with acute and recurrent diabetic gastric stasis.

Intravenous administration of Reglan Injection diluted in a parenteral solution should be made slowly over a period of not less than 15 minutes.

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keep reglan out of the reach of children and away from pets.

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