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This medicine can pass into body fluidsurinefecesvomitCaregivers should wear rubber gloves while cleaning up a patient’s body fluidshandling contaminated trash or laundry or changing diapersWash hands before and after removing glovesWash soiled clothing and linens separately from other laundry.

Concomitant administration of cholestyramine with EVISTA is not recommendedAlthough not specifically studiedit is anticipated that other anion exchange resins would have a similar effectEVISTA should not be co-administered with other anion exchange resinssee CLINICAL PHARMACOLOGY

EVISTA should not be used by lactating womensee CONTRAINDICATIONSIt is not known whether this drug is excreted in human milkBecause many drugs are excreted in human milkcaution should be exercised when raloxifene is administered to a nursing woman.

EVISTA should be used with caution in patients with moderate or severe renal impairmentsee WARNINGS AND PRECAUTIONS and CLINICAL PHARMACOLOGY

Reason for postingRaloxifene is used for the treatment and prevention of osteoporosisIt is a selective estrogen-receptor modulator with estrogen-agonist effects on bone and lipid metabolism but not the breasts and uterusThe drug’s effect on a woman’s risk of cardiovascular events and risk of invasive breast cancer was assessed in the RUTHRaloxifene Use for The HearttrialThe drug’s manufacturer recently disclosed that women taking the drug in the trial had an increased risk of death from stroke1.

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