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This study compared the tolerability of weekly mefloquine, weekly mefloquine following a loading dose, and weekly chloroquine in 359 us marines over a 12 week period.

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Call a poison control center at once and then seek emergency medical attention if you think you have used too much of this medicineAn overdose of chloroquine can be fatalespecially in children.

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Chloroquine is active against the erythrocytic forms of Plasmodium vivaxPlasmodium malariaeand susceptible strains of Plasmodium falciparumbut not the gametocytes of PfalciparumIt is not effective against exoerythrocytic forms of the parasite.

Patients infected with a resistant strain of plasmodia as shown by the fact that normally adequate doses have failed to prevent or cure clinical malaria or parasitemia should be treated with another form of antimalarial therapy.

Chloroquine is used to treat and to prevent malariaChloroquine is also used to treat infections caused by amoebae.

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